Pyrazine ni heterocyclic harufu kiwanja kikaboni na formula kemikali C4H4N2.

Pyrazine ni molekuli ya kawaida na kundi la D2h. Pyrazine ni chini ya msingi kuliko pyridine, pyridazine na pyrimidine.

Derivatives kama vile phenazine hujulikana kwa shughuli zao za kupinga, antibiotic na diuretic.

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